Portfolio

Provider of a new type of high-power lithium-ion batteries designed to improve energy and power density.

AFOP designs, manufactures, and markets a broad range of high performance fiber optic components and integrated modules for the optical network equipment market.

AirTight® Networks enables enterprises and service providers to maintain network and mobile client integrity from wireless security vulnerabilities whether or not they deploy a wireless network. AirTight Networks offers the industry's first wireless IPS (WIPS) that delivers around-the-clock wireless monitoring and automatic intrusion prevention as well as manages wireless network performance for maximum capacity and uptime.

Alexza uses its proprietary technology to enable faster onset of drugs. Faster onset provides rapid relief of acute and episodic symptoms.

Based on a revolutionary means of packaging custom circuits called NanoBlock® ICs, Alien is using its high volume roll-to-roll process to produce low cost radio frequency tags, in which a small integrated wireless circuit is used to identify objects remotely.

Altus® is focused on accelerating the development and commercialization of protein-based products through our Crystalomics™ technology platform. Crystalomics™ rapidly turns proteins into products resulting in significant market benefits in Therapeutic, Diagnostic, and Industrial applications.

Ambrx, Inc. is a biopharmaceutical company with a mission to deliver breakthrough protein therapeutics. Ambrx is based on a fundamental advance in protein biosynthesis that enables the company to genetically engineer proteins with new amino acid building blocks beyond the common twenty, enabling the biosynthesis of proteins with new physical, chemical and pharmacological properties.

Amitive, Inc. is the leading provider of on-demand, community supply chain management for virtual manufacturers. Amitive, initially known as Mitrix, is a private company based in Redwood City, California.

Anesiva, Inc. (Nasdaq: ANSV) is a late-stage biopharmaceutical company focused on the development and commercialization of novel pharmaceutical products for pain management. Our lead product, Adlea, is a long-acting, local, non-opioid analgesic in late-stage clinical development for the management of post-operative pain associated with orthopedic surgery and which also has potential in the treatment of pain in general surgery, some localized sites of pain, and due to moderate-to-severe osteoarthritis.

Applied Wave Research, Inc., (AWR) is a worldwide leader in high-frequency electronic design automation (EDA) software for wireless, high-speed wireline, and electro-optical applications. The company's mission is to dramatically accelerate time-to-market and reduce product development costs for its customers.

Apriso is the world's premier provider of plant and warehouse automation solutions for the industrial sector. We offer proven state-of-the-art products, technologies and expertise for automating your operations, and integrating them with your electronic commerce and ERP systems.

Arcadia Biosciences (acquired CMEA portfolio company Anawah) is developing agricultural products to capitalize on opportunities that benefit the environment and enhance human health. The company uses advanced screening, breeding and biotechnology techniques to create value for consumers, processors and farmers.

Arcion Therapeutics Inc. is a clinical stage biotechnology company focused on the development of new, targeted treatments for severe pain. Arcion has a pipeline of products being developed for the treatment of painful diabetic neuropathy, post-herpetic neuralgia and other forms of moderate and severe pain.

Ardelyx™ develops therapeutics acting exclusively in the gastrointestinal tract and devoid of systemic exposure. Our drug candidates target important diseases, as well as pathologies with a specific inflammatory pathway. Our technology relies on non-absorbable small molecules with highly specific modes of action. The quasi-absence of systemic uptake greatly reduces potential side effects and toxicity while concentrating the drug at the locus of action, i.e. the GI tract.

The vision of Auspex Pharmaceuticals is to be the leading deuteration company with a developing pipeline of best-in-class therapeutics that improve on existing drugs across multiple therapeutic areas.

Bayhill Therapeutics is focused on the translation of research into therapeutics for the treatment of autoimmune diseases. The company has established a therapeutic platform of autoimmune modulators, in-licensed from Stanford University, that address the broad market opportunity of Th1 mediated autoimmune diseases.

Biolex is a clinical-stage biopharmaceutical company that uses its patented LEX System^SM to develop hard-to-make therapeutic proteins and to optimize monoclonal antibodies. The LEX System is a novel technology that genetically transforms the aquatic plant Lemna to enable the production of biologic product candidates. The company's product candidates are designed to provide superior efficacy/tolerability profiles and to address large, proven pharmaceutical markets. Biolex's lead product candidate, Locteron®, is in Phase 2b clinical testing for the treatment of chronic hepatitis C, a market projected to grow to $6 billion. Locteron, controlled-release interferon alpha 2b, is designed to improve patient care by providing a more convenient once-every-two week dosing schedule and by reducing the side effects, including flu-like symptoms, associated with pegylated interferons, the current standard of care. Biolex has also developed two other product candidates that capitalize on the benefits of the LEX System which it is advancing toward clinical trials: BLX-155, a direct-acting thrombolytic designed to dissolve blood clots in patients; and BLX-301, an anti-CD20 antibody it is optimizing for the treatment of non- Hodgkin's B-cell lymphoma and other diseases.

Biolight Harvesting is developing photosynthetic bacteria as part of an integrated production platform for making renewable fuels and chemicals.

BioMimetic Pharmaceuticals, Inc. (BMTI) is a biopharmaceutical company focused on the development, commercialization and ultimate marketing of protein therapeutics for tissue and organ regeneration. The Company's lead technologies are for the healing and restoration of bone and other tissues. Its lead products are based on recombinant human platelet-derived growth factor BB (rhPDGF-BB).

CafePress is the leader in User-Generated Commerce and offers sellers turnkey e-commerce services to independently create and sell a wide variety of products, and offers buyers unique merchandise across virtually every topic. Launched in 1999, CafePress has empowered individuals, organizations and businesses to create, buy and sell customized merchandise online using the company's unique print-on-demand and e-commerce services. Today, CafePress is a growing network of over 6.5 million members who have unleashed their creativity to transform their artwork and ideas into unique gifts and new revenue streams.

CFX Battery, Inc. is a start up advanced battery company that is focused on developing and commercializing new, innovative and disruptive battery products.

Cnano Technology Limited develops and manufactures carbon nanotubes and related products for diverse applications across broad market segments including energy, environmental/cleantech, specialty materials, and electronics.

Codexis is leading the way with powerful biocatalysts that integrate biology and chemistry. Codexis makes production of pharmaceuticals, biofuels and industrial products faster, cleaner and less expensive.

Danotek Motion Technologies develops and manufactures advanced permanent magnet (PM) generators and electric power conditioning systems for clean energy applications.

Draths Corporation is a next generation chemical company focused on manufacturing bio-based materials used in everyday products. The company's products, rooted in its platform technology, enable nylons, plastics, paints, resins, and other materials currently made from petroleum-based chemicals to be manufactured from renewable feedstocks. For more information , please visit

Ensemble Discovery Corporation is an early stage company founded by scientists and entrepreneurs who have come together to translate fundamental innovation in chemical discovery into products that address significant unmet needs in life science, materials, electronics, and chemical markets.

As a leading provider of hosting automation solutions, Ensim offers software solutions, management tools and hosted services, to enable Service Providers to efficiently deliver hosted services to small and medium businesses.

Entropic (acquired CMEA portfolio company RF Magic) is a fabless semiconductor company that will fundamentally change the way video and other broadband multimedia forms are used in homes.

EPIX Pharmaceuticals is a biopharmaceutical company focused on discovering, developing and commercializing novel pharmaceutical products through the use of proprietary technology to better diagnose, treat and manage patients.

Leading providers of a robotic operating systems with modular solutions for autonomous navigation as well as man-machine interaction and integration.

HassoPlattnerVentures converts creative ideas in the software sector into sustainable economic success. The fund's basic approach is to offer IT-start-ups a new and unique environment of financial backing, consulting, and logistical support. HPV hosts a certain number of young, IT-driven companies and guides them into the marketplace, leading to new impulses for growth and employment.

InSound is marketing the only FDA approved "extended wear" hearing solution, which is virtually invisible, extremely comfortable, has no batteries to change, no daily inserting and removing, and also offers excellent hearing benefits including increased high frequency amplification, decreased distortion, better localized sound, and reduced feedback and occlusion.

Intellikine is developing small molecule therapies targeting the PI3K/mTOR pathway for treatment of cancer, inflammation and autoimmune diseases.

Intermolecular's High-Productivity Combinatorial (HPC) methods, systems and software provide their IC customers a unique competitive advantage by accelerating integration learning in the development and commercialization of advanced materials, process, and device solutions - at an order of magnitude lower cost than conventional methods.

Inventure Chemical has developed processes for the direct, efficient production of industrial bio-chemicals and fuels from materials such as algae, agricultural by-products and waste biomass.

Combining leading technologies with the market intelligence and expertise of the industry's most skilled procurement, fulfillment, logistics, and supply chain professionals -- iSuppli is revolutionizing the electronic component supply chain with agile, efficient and reliable supply chain solutions and services.

The on demand recruitment application that's radically easy to use for everyone involved in hiring

Kalypsys, Inc. is a biopharmaceutical company pioneering an industrialized approach to pathway-based drug discovery. Kalypsys implements discovery programs across a broad number of therapeutic areas using its highly automated and integrated suite of discovery technologies in biology, chemistry and informatics.

LiveOps has developed a robust and scalable teleservices solution backed by the same technologies that power Internet giants such as Google, eBay, and Yahoo!. Since LiveOps built and owns 100% of the systems they use, LiveOps can bring a flexibility and efficiency in working with its clients that no other teleservices company can match.

Luminus Devices, Inc. develops and manufactures high performance solid state light sources for a variety of illumination applications.

Founded in 2000, MacroGenics is a private, fully-integrated biotechnology company headquartered in Rockville, Maryland, that focuses on the development, manufacture, and commercialization of immunotherapeutics for autoimmune disorders, cancer, and infectious diseases. In October 2007, MacroGenics, Inc. and Eli Lilly and Company announced a global strategic alliance to develop and commercialize teplizumab, a humanized anti-CD3 monoclonal antibody, as well as other potential next-generation anti-CD3 molecules for use in the treatment of autoimmune diseases. Teplizumab is currently being studied in the PROTÉGÉ trial, a global pivotal Phase II/III clinical trial for individuals with recent-onset Type 1 diabetes. In July 2008, MacroGenics acquired Raven Biotechnologies, Inc., a privately held biotechnology company in South San Francisco, California, focused on the discovery and development of monoclonal antibody therapeutics for oncology through its cancer stem-like cell program. MacroGenics' proprietary DART (Dual Affinity Re-Targeting) and Fc-optimization technologies offer ways to improve the function of antibodies and similar molecules. For more information about MacroGenics, please visit

MailExpress provides an outsourced mail service for large commercial mailers throughout the world. Their services include mail sorting, managing customer lists with proprietary technology, and expedited delivery of mail consisting of marketing and promotional materials. MailExpress provides it customers a rapid delivery of flat mail with lower costs than first class mail.

Monogram (acquired CMEA portfolio company Virologic) is a leader in developing and commercializing innovative products to help guide and improve the treatment of infectious diseases, cancer and other serious diseases.

Multigig is a fabless semiconductor supplier that has developed a fundamental advance in semiconductor circuit technology that enables new levels of performance while dramatically lowering power. With 22 patents granted and more than 50 pending, the company's RotaryWave(tm) technology is being incorporated into new architectures for leading-edge semiconductor products.

NEA-IndoUS Ventures provides early and mid-stage funding to new or growing technology businesses in India. The team comprises experienced entrepreneurs and executives who understand the model of incubating ideas and transforming them into successful enterprises.

Invented by the visionary behind the original QuickBooks, NetBooks was created specifically for inventory-based businesses with two to fifty people. NetBooks unites technology, people, and partners into one powerful solution for small business owners who are looking to improve the efficiency and productivity of their operations.

NuScale is a developer of modular scale nuclear power generation technology.

Paul Lorenzini, PhD
Chief Executive Officer
NuScale Power Inc.
503-292-2691

Odyssey Logistics & Technology provides outsourced logistics management services to the chemical industry and other process manufacturers. Odyssey allows companies to outsource the management and transportation of raw materials and finished goods, thereby helping customers achieve savings through reduced infrastructure costs, adding process improvements, and enhancing customer service, data quality and management.

Innovative oil drilling technology

Perlegen Sciences, Inc. is a private company that uses high-density, whole-wafer microarray technology in combination with new approaches to sample preparation to scan entire human genomes. The company's first objective is to read 50 different human genomes at a single base resolution, discovering and analyzing the patterns of genetic variation between them.

Phenomix is a forward genetics company focusing on rapid target identification and validation. Phenomix's approach to the identification of pathways important in clinical disease relies on classical genetics coupled to the recent advances of the genome project. Phenomix starts from rapidly generating and screening physiological models to identify the best disease models and then in a single step, discovers and validates the genes that are physiologically relevant. Phenomix combines target discovery, target validation, and generation of relevant models for the disease into one efficient platform.

Ultralow cost flexible photovoltaic cells

Founded in 2008, Pixazza, Inc. provides an internet service that turns static images into engaging content, while generating incremental income for web publishers. Pixazza enables consumers to simply mouse over images on their favorite web sites to learn more and see related products. Pixazza is a private company funded by August Capital, CMEA Ventures, and Google, with offices in Mountain View, CA. For more information, visit

Pyxis Technology, Inc is a privately held company headquartered in Austin, Texas. Pyxis Technology develops and markets EDA software for chip design and analysis, primarily focused on design closure, manufacturability, and time-to-market issues for sub-100nm process technologies.

Rigel is a clinical-stage drug development company that discovers and develops novel, small-molecule drugs for the treatment of inflammatory/autoimmune diseases and cancer, as well as viral and metabolic diseases.

Schooner Information Technology, Inc. is an early stage startup focused on delivering next generation data access solutions for Web 2.0 and enterprise customers.

Solyndra's breakthrough, proprietary photovoltaic systems for commercial rooftops employ a new cylindrical module geometry which enables greatly lower installation costs and significantly higher annual solar electricity output per rooftop at a lower cost of electricity.

Sorbent Therapeutics is developing a treatment for end stage renal disease patients undergoing dialysis.

Don Joseph, CEO
Sorbent Therapeutics, Inc.
750 E. Bunker Court, Suite 900
Vernon Hills, Il. 60061-1863
847-890-1130 (phone)
847-680-9216 (fax)

SpikeSource is a software company that distributes, manages, integrates, and supports open source solutions across the enterprise.

Superprotonic is an energy technology company established to market and commercialize the innovative solid acid fuel cell (SAFC) technology developed and patented by the company's founders at the California Institute of Technology.

SurgiQuest develops and markets access devices and other instruments for laparascopic surgery.

Symwave is a fabless semiconductor company that designs, develops, and markets high-performance analog/mixed signal integrated circuits (ICs) and system solutions.

Developer of a proprietary technology platform in combinatorial materials science to discover and improve materials for the chemical and electronics industries.

Capitalizing on breakthrough synthetic chemistry, Tetraphase Pharmaceuticals is leveraging a dynamic drug engine targeted at several significant disease categories.

Triporati was founded by a team of online travel veterans who set out to help travelers answer the fundamental question "Where should I go?" More than 70 percent of leisure travelers don't know where they will travel six months prior to their trip, yet existing travel sites begin by asking users where they will go. To address this need, and to help travelers discover great trips, Triporati has built a proprietary destination discovery engine powered by original content and rankings from 65 bona fide travel experts who have collectively written or edited more than 550 best-selling guidebooks (such as Lonely Planet, Frommer's, Fodor's and more). By ranking their own unique interests, travelers are presented with personalized world maps showing their ideal travel destinations. Triporati was recognized as one of the top six travel innovators at the 2008 PhocusWright Travel Innovation Summit.

TrueDemand Software is a pioneer in the development of new supply chain applications that take advantage of both RFID and non-RFID data to help solve supply chain planning and execution problems.

Untangle (fka Metavize) is an emerging leader in network virtualization for small- to medium-sized enterprises (SMEs) seeking powerful yet simple and easy-to-use network solutions. Founded in 2003, the company intends to fulfill its vision by designing an innovative technology to address and overcome the limitations of existing network solutions.

VasoNova is a medical device company developing a guidance systems for catheter insertion, initially for the insertion of percutaneously inserted central catheters (PICC lines).

VeraLight is a medical instrumentation company that was established in October 2004 as an independent spinout of InLight Solutions to focus on a comprehensive approach to noninvasive diabetes screening.

Visiogen is focused on developing innovative products for cataract and refractive patients. Founded in Irvine, California, in 2001, Visiogen's first commercial application, Synchrony®, a dual-optic intraocular lens and pre-loaded injector, is currently in clinical studies in the U.S. and recently received a CE Mark in Europe.

Wildcat Discovery Technologies is focused on the discovery of energy-related, solid-state materials. The company utilizes high throughput synthesis and characterization technologies, and is initially targeting materials for hydrogen storage.

Developer of new molecular-based technology for enhancing the oral absorption, distribution, and pharmacokinetics of drugs.